{
  "schema_version": "2.0",
  "record_type": "dataset",
  "tier": "verified",
  "slug": "kegg",
  "name": "KEGG: Kyoto Encyclopedia of Genes and Genomes",
  "summary": {
    "en": "License: restricted (LicenseRef-Kanehisa-Laboratories-terms); Mdexa hosting: link-only. Second pass: redistribution: [甲类] 学术用户利用 KEGG 对外提供服务也须取得学术服务提供者许可（含于 FTP 学术订阅）；向他人提供被涉及且须另行授权，应为 conditional。",
    "zh": "许可证声明：受限（LicenseRef-Kanehisa-Laboratories-terms）；本站处理：只链接原出处。第二遍复核：redistribution: [甲类] 学术用户利用 KEGG 对外提供服务也须取得学术服务提供者许可（含于 FTP 学术订阅）；向他人提供被涉及且须另行授权，应为 conditional。。"
  },
  "systems": [
    "modern-medicine"
  ],
  "domains": [
    "genomics-omics"
  ],
  "content_types": [
    "database"
  ],
  "content_description": {
    "en": "KEGG (Kyoto Encyclopedia of Genes and Genomes) is an original database product of Kanehisa Laboratories; academic users may freely use the website; non-academic use requires a commercial license.",
    "zh": "KEGG（京都基因与基因组百科全书）是Kanehisa Laboratories的原创数据库产品；学术用户可自由使用其网站，非学术使用需获得商业许可。"
  },
  "languages": [
    "en"
  ],
  "modalities": [
    "text"
  ],
  "size": {
    "raw": null,
    "measures": []
  },
  "publisher": "Kanehisa Laboratories",
  "year": {
    "value": null,
    "raw": null
  },
  "license": {
    "legacy_status": "pending",
    "spdx": "LicenseRef-Kanehisa-Laboratories-terms",
    "commercial_use": "conditional",
    "derivatives": "unstated",
    "redistribution": "conditional",
    "rationale": {
      "en": "a restricted part cannot be separated or the boundary is unstated: strictest part applies",
      "zh": "受限的部分无法分离或边界未说明，取最严"
    },
    "evidence": [
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s02 (page)",
          "zh": "在快照 s02（page）中找到的声明"
        },
        "excerpt": "KEGG is an original database product, copyright Kanehisa Laboratories.",
        "url": "https://www.kegg.jp/kegg/legal.html",
        "verified_on": "2026-11-13",
        "snapshot_id": "s02",
        "observed": "page",
        "captured_by": "pipeline"
      },
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s02 (page)",
          "zh": "在快照 s02（page）中找到的声明"
        },
        "excerpt": "Although best efforts are always applied when developing KEGG products, Kanehisa Laboratories makes no warrant nor assumes any legal responsibility for the accuracy or usefulness of KEGG or any information contained therein.",
        "url": "https://www.kegg.jp/kegg/legal.html",
        "verified_on": "2026-11-13",
        "snapshot_id": "s02",
        "observed": "page",
        "captured_by": "pipeline"
      },
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s02 (page)",
          "zh": "在快照 s02（page）中找到的声明"
        },
        "excerpt": "Academic users may freely use the KEGG website at https://www.kegg.jp/ or its mirror site at GenomeNet https://www.genome.jp/kegg/ .",
        "url": "https://www.kegg.jp/kegg/legal.html",
        "verified_on": "2026-11-13",
        "snapshot_id": "s02",
        "observed": "page",
        "captured_by": "pipeline"
      },
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s02 (page)",
          "zh": "在快照 s02（page）中找到的声明"
        },
        "excerpt": "Academic users who utilize KEGG for providing services are requested to obtain an academic service provider license, which is included in the KEGG FTP academic subscription .",
        "url": "https://www.kegg.jp/kegg/legal.html",
        "verified_on": "2026-11-13",
        "snapshot_id": "s02",
        "observed": "page",
        "captured_by": "pipeline"
      },
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s02 (page)",
          "zh": "在快照 s02（page）中找到的声明"
        },
        "excerpt": "Non-academic users must understand that KEGG is not a public database, nor is it a publicly funded database.",
        "url": "https://www.kegg.jp/kegg/legal.html",
        "verified_on": "2026-11-13",
        "snapshot_id": "s02",
        "observed": "page",
        "captured_by": "pipeline"
      },
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s02 (page)",
          "zh": "在快照 s02（page）中找到的声明"
        },
        "excerpt": "Non-academic use of KEGG requires a commercial license.",
        "url": "https://www.kegg.jp/kegg/legal.html",
        "verified_on": "2026-11-13",
        "snapshot_id": "s02",
        "observed": "page",
        "captured_by": "pipeline"
      },
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s02 (page)",
          "zh": "在快照 s02（page）中找到的声明"
        },
        "excerpt": "Please contact Pathway Solutions , which operates KEGG FTP sites and a KEGG mirror website, for license agreements.",
        "url": "https://www.kegg.jp/kegg/legal.html",
        "verified_on": "2026-11-13",
        "snapshot_id": "s02",
        "observed": "page",
        "captured_by": "pipeline"
      },
      {
        "location": "dataset-page",
        "location_detail": {
          "en": "Statement found in snapshot s10 (page)",
          "zh": "在快照 s10（page）中找到的声明"
        },
        "excerpt": "The KEGG FTP site for academic users is available to subscribers only.",
        "url": "https://www.kegg.jp/kegg/download/",
        "verified_on": "2026-11-13",
        "snapshot_id": "s10",
        "observed": "page",
        "captured_by": "browser-agent",
        "capturer": "browser-agent",
        "captured_at": "2026-11-14",
        "page_title": "KEGG FTP",
        "final_url": "https://www.kegg.jp/kegg/download/",
        "text_sha256": "dbcdacaa3547e6092fdb42078ee60e4825e048528ce5a6166ff8112e0e30880e"
      },
      {
        "location": "dataset-page",
        "location_detail": {
          "en": "Statement found in snapshot s10 (page)",
          "zh": "在快照 s10（page）中找到的声明"
        },
        "excerpt": "A subset of KEGG MEDICUS is freely available at the GenomeNet FTP site.",
        "url": "https://www.kegg.jp/kegg/download/",
        "verified_on": "2026-11-13",
        "snapshot_id": "s10",
        "observed": "page",
        "captured_by": "browser-agent",
        "capturer": "browser-agent",
        "captured_at": "2026-11-14",
        "page_title": "KEGG FTP",
        "final_url": "https://www.kegg.jp/kegg/download/",
        "text_sha256": "dbcdacaa3547e6092fdb42078ee60e4825e048528ce5a6166ff8112e0e30880e"
      },
      {
        "location": "dataset-page",
        "location_detail": {
          "en": "Statement found in snapshot s10 (page)",
          "zh": "在快照 s10（page）中找到的声明"
        },
        "excerpt": "Non-academic users are requested to obtain a license agreement for using KEGG.",
        "url": "https://www.kegg.jp/kegg/download/",
        "verified_on": "2026-11-13",
        "snapshot_id": "s10",
        "observed": "page",
        "captured_by": "browser-agent",
        "capturer": "browser-agent",
        "captured_at": "2026-11-14",
        "page_title": "KEGG FTP",
        "final_url": "https://www.kegg.jp/kegg/download/",
        "text_sha256": "dbcdacaa3547e6092fdb42078ee60e4825e048528ce5a6166ff8112e0e30880e"
      },
      {
        "location": "website-footer",
        "location_detail": {
          "en": "Statement found in snapshot s10 (page)",
          "zh": "在快照 s10（page）中找到的声明"
        },
        "excerpt": "Copyright 1995-2026 Kanehisa Laboratories",
        "url": "https://www.kegg.jp/kegg/download/",
        "verified_on": "2026-11-13",
        "snapshot_id": "s10",
        "observed": "page",
        "captured_by": "browser-agent",
        "capturer": "browser-agent",
        "captured_at": "2026-11-14",
        "page_title": "KEGG FTP",
        "final_url": "https://www.kegg.jp/kegg/download/",
        "text_sha256": "dbcdacaa3547e6092fdb42078ee60e4825e048528ce5a6166ff8112e0e30880e"
      },
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s04 (page)",
          "zh": "在快照 s04（page）中找到的声明"
        },
        "excerpt": "Restriction: KEGG API at rest.kegg.jp is made available only for academic use by academic users.",
        "url": "https://www.kegg.jp/kegg/rest/",
        "verified_on": "2026-11-13",
        "snapshot_id": "s04",
        "observed": "page",
        "captured_by": "pipeline"
      },
      {
        "location": "terms-page",
        "location_detail": {
          "en": "Statement found in snapshot s04 (page)",
          "zh": "在快照 s04（page）中找到的声明"
        },
        "excerpt": "Please limit your API calls up to 3 times per second.",
        "url": "https://www.kegg.jp/kegg/rest/",
        "verified_on": "2026-11-13",
        "snapshot_id": "s04",
        "observed": "page",
        "captured_by": "pipeline"
      }
    ],
    "license_parts": [
      {
        "name": {
          "en": "main data",
          "zh": "主体数据"
        },
        "spdx": "NOASSERTION",
        "status": "restricted",
        "separable": true,
        "evidence": {
          "excerpt": "KEGG is an original database product, copyright Kanehisa Laboratories.",
          "url": "https://www.kegg.jp/kegg/legal.html",
          "snapshot_id": "s02"
        }
      },
      {
        "name": {
          "en": "KEGG website",
          "zh": "KEGG website"
        },
        "spdx": "NOASSERTION",
        "status": "permissive",
        "separable": true,
        "evidence": {
          "excerpt": "Academic users may freely use the KEGG website at https://www.kegg.jp/ or its mirror site at GenomeNet https://www.genome.jp/kegg/ .",
          "url": "https://www.kegg.jp/kegg/legal.html",
          "snapshot_id": "s02"
        }
      },
      {
        "name": {
          "en": "KEGG MEDICUS",
          "zh": "KEGG MEDICUS"
        },
        "spdx": "NOASSERTION",
        "status": "permissive",
        "separable": true,
        "evidence": {
          "excerpt": "A subset of KEGG MEDICUS is freely available at the GenomeNet FTP site.",
          "url": "https://www.kegg.jp/kegg/download/",
          "snapshot_id": "s10"
        }
      },
      {
        "name": {
          "en": "KEGG FTP",
          "zh": "KEGG FTP"
        },
        "spdx": "NOASSERTION",
        "status": "restricted",
        "separable": true,
        "evidence": {
          "excerpt": "The KEGG FTP site for academic users is available to subscribers only.",
          "url": "https://www.kegg.jp/kegg/download/",
          "snapshot_id": "s10"
        }
      }
    ],
    "custom_license": true,
    "review": {
      "method": "rules-plus-second-pass-model",
      "method_label": {
        "en": "Judged by public rules and checked a second time before listing.",
        "zh": "按公开规则判定，经二次核对后收录。"
      },
      "readings": [
        {
          "restatement": {
            "en": "a restricted part cannot be separated or the boundary is unstated: strictest part applies",
            "zh": "受限的部分无法分离或边界未说明，取最严"
          },
          "quotes": [
            {
              "excerpt": "KEGG is an original database product, copyright Kanehisa Laboratories.",
              "snapshot_id": "s02",
              "url": "https://www.kegg.jp/kegg/legal.html"
            },
            {
              "excerpt": "Although best efforts are always applied when developing KEGG products, Kanehisa Laboratories makes no warrant nor assumes any legal responsibility for the accuracy or usefulness of KEGG or any information contained therein.",
              "snapshot_id": "s02",
              "url": "https://www.kegg.jp/kegg/legal.html"
            },
            {
              "excerpt": "Academic users may freely use the KEGG website at https://www.kegg.jp/ or its mirror site at GenomeNet https://www.genome.jp/kegg/ .",
              "snapshot_id": "s02",
              "url": "https://www.kegg.jp/kegg/legal.html"
            },
            {
              "excerpt": "Academic users who utilize KEGG for providing services are requested to obtain an academic service provider license, which is included in the KEGG FTP academic subscription .",
              "snapshot_id": "s02",
              "url": "https://www.kegg.jp/kegg/legal.html"
            }
          ],
          "values": {
            "license_status": "restricted",
            "commercial_use": "conditional",
            "derivatives": "unstated",
            "redistribution": "unstated"
          },
          "source": "rules"
        },
        {
          "restatement": {
            "en": "Second pass: redistribution: [甲类] 学术用户利用 KEGG 对外提供服务也须取得学术服务提供者许可（含于 FTP 学术订阅）；向他人提供被涉及且须另行授权，应为 conditional。",
            "zh": "第二遍复核：redistribution: [甲类] 学术用户利用 KEGG 对外提供服务也须取得学术服务提供者许可（含于 FTP 学术订阅）；向他人提供被涉及且须另行授权，应为 conditional。"
          },
          "quotes": [
            {
              "excerpt": "Non-academic use of KEGG requires a commercial license.",
              "snapshot_id": "s02",
              "url": null
            },
            {
              "excerpt": "Restriction: KEGG API at rest.kegg.jp is made available only for academic use by academic users.",
              "snapshot_id": "s04",
              "url": null
            },
            {
              "excerpt": "Please contact Pathway Solutions , which operates KEGG FTP sites and a KEGG mirror website, for license agreements.",
              "snapshot_id": "s02",
              "url": null
            },
            {
              "excerpt": "KEGG is an original database product, copyright Kanehisa Laboratories.",
              "snapshot_id": "s02",
              "url": null
            }
          ],
          "values": {
            "license_status": "restricted",
            "commercial_use": "conditional",
            "derivatives": "unstated",
            "redistribution": "conditional"
          },
          "source": "second-pass"
        }
      ],
      "adopted": 1,
      "second_pass": {
        "reviewer": "model-second-pass",
        "reviewed_at": "2026-11-14",
        "overall": "stricter",
        "agreed": false,
        "disagreement": {
          "en": "Second pass: redistribution: [甲类] 学术用户利用 KEGG 对外提供服务也须取得学术服务提供者许可（含于 FTP 学术订阅）；向他人提供被涉及且须另行授权，应为 conditional。",
          "zh": "第二遍复核：redistribution: [甲类] 学术用户利用 KEGG 对外提供服务也须取得学术服务提供者许可（含于 FTP 学术订阅）；向他人提供被涉及且须另行授权，应为 conditional。"
        },
        "missed_restrictions": [
          {
            "excerpt": "Restriction: KEGG API at rest.kegg.jp is made available only for academic use by academic users.",
            "snapshot_id": "s04",
            "effect": "[甲类] API 仅限学术用户学术使用：支持 restricted；第一遍未入证据。",
            "class": "A"
          },
          {
            "excerpt": "Please limit your API calls up to 3 times per second.",
            "snapshot_id": "s04",
            "effect": "[乙类] 访问频率义务：license_conditions 加 conduct-restrictions，不改状态。",
            "class": "D"
          }
        ],
        "routing": [
          "missed sentence, class A: Restriction: KEGG API at rest.kegg.jp is made available only for academic use by academic ",
          "missed sentence, class D: Please limit your API calls up to 3 times per second."
        ]
      }
    }
  },
  "license_status": "restricted",
  "hosting": "link-only",
  "hosting_reason": {
    "en": "License restricted, judged by public rules and checked by a second-pass model. Link only.",
    "zh": "许可证状态：restricted，按公开规则判定并经第二遍模型复核。仅链接。"
  },
  "signoff": null,
  "risk_flags": [],
  "provenance": {
    "source_description": null,
    "upstream": []
  },
  "known_issues": [],
  "usage_notes": [
    {
      "kind": "disclaimer",
      "excerpt": "Although best efforts are always applied when developing KEGG products, Kanehisa Laboratories makes no warrant nor assumes any legal responsibility for the accuracy or usefulness of KEGG or any information contained therein.",
      "url": "https://www.kegg.jp/kegg/legal.html",
      "snapshot_id": "s02"
    }
  ],
  "preflight": {
    "status": "not-run"
  },
  "access": {
    "mdexa_download": null,
    "external_urls": [
      "https://www.kegg.jp/",
      "https://www.kegg.jp/kegg/legal.html"
    ],
    "notes": null
  },
  "citation": {
    "text": null,
    "references": []
  },
  "verification_level": "verified",
  "last_verified": "2026-11-14",
  "changelog": [
    {
      "date": "2026-11-14",
      "change": {
        "en": "Listed on 2026-11-14. Judged by public rules and checked a second time before listing. The two passes disagreed; the stricter reading is carried: Second pass: redistribution: [甲类] 学术用户利用 KEGG 对外提供服务也须取得学术服务提供者许可（含于 FTP 学术订阅）；向他人提供被涉及且须另行授权，应为 conditional。",
        "zh": "2026-11-14 上架。按公开规则判定，经二次核对后收录。两遍判定不一致，卡上取较严的读法：第二遍复核：redistribution: [甲类] 学术用户利用 KEGG 对外提供服务也须取得学术服务提供者许可（含于 FTP 学术订阅）；向他人提供被涉及且须另行授权，应为 conditional。"
      }
    }
  ],
  "practical": {
    "content_scope": {
      "entities": [
        {
          "kind": "database product",
          "count": null,
          "count_as_of": null,
          "statement": {
            "text": {
              "en": "KEGG is an original database product, copyright Kanehisa Laboratories.",
              "zh": "KEGG 是一个原创数据库产品，版权归 Kanehisa Laboratories。"
            },
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "KEGG is an original database product, copyright Kanehisa Laboratories.",
                "url": "https://www.kegg.jp/kegg/legal.html",
                "snapshot_id": "s02",
                "char_start": 87,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        }
      ],
      "coverage": []
    },
    "identifiers": {
      "schemes": [
        {
          "name": "KEGG DRUG D numbers under YK codes",
          "bioregistry_prefix": null,
          "applies_to": "prescription drug products marketed in Japan",
          "statement": {
            "text": {
              "en": "All prescription drug products marketed in Japan are given KEGG DRUG D numbers under the classification of 9-character codes named YK codes.",
              "zh": "在日本上市的所有处方药产品都按名为 YK 代码的 9 字符代码分类，获得 KEGG DRUG D 编号。"
            },
            "evidence": [
              {
                "location": "api-doc",
                "excerpt": "All prescription drug products marketed in Japan are given KEGG DRUG D numbers under the classification of 9-character codes named YK codes",
                "url": "https://www.kegg.jp/kegg/docs/relnote.html",
                "snapshot_id": "s03",
                "char_start": 4115,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        }
      ],
      "crosswalks": [
        {
          "to": "NCBI taxonomy",
          "to_slug": null,
          "statement": {
            "text": {
              "en": "NCBI taxonomy IDs are used for individual KEGG organisms and for organism groups at different taxonomic ranks, and links to and from KEGG organism codes or T numbers are made available in the KEGG API.",
              "zh": "NCBI 分类学 ID 不仅用于单个 KEGG 生物体，也用于不同分类层级上的生物体组；KEGG API 提供与 KEGG 生物体代码或 T 编号之间的双向链接。"
            },
            "evidence": [
              {
                "location": "api-doc",
                "excerpt": "NCBI taxonomy IDs are used not only for individual KEGG organisms, but also for organism groups at different levels of taxonomic ranks. Links to/from KEGG organism codes (or T numbers) are made available in KEGG API.",
                "url": "https://www.kegg.jp/kegg/docs/relnote.html",
                "snapshot_id": "s03",
                "char_start": 2542,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        },
        {
          "to": "YK code",
          "to_slug": null,
          "statement": {
            "text": {
              "en": "The API update history for December 1, 2024 states that the YK code was included as an outside identifier.",
              "zh": "API 更新历史中 2024 年 12 月 1 日条目说明 YK 代码作为外部标识符被纳入。"
            },
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "December 1, 2024 YK code included as an outside identifier",
                "url": "https://www.kegg.jp/kegg/rest/",
                "snapshot_id": "s04",
                "char_start": 1122,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        }
      ],
      "mismatch_cases": [],
      "notes": [
        {
          "text": {
            "en": "Organism-specific pathway maps are computationally generated from manually drawn reference maps, e.g. map01100 to hsa01100.",
            "zh": "物种特异通路图由人工绘制的参考图计算生成，如由 map01100 生成 hsa01100。"
          },
          "evidence": [
            {
              "location": "peer-reviewed-paper",
              "excerpt": "For the three databases in the systems information category, PATHWAY, BRITE and MODULE, the molecular network objects of pathway maps, Brite hierarchies and KEGG modules are expanded from manually created reference objects to computationally generated organism-specific objects, such as from map01100",
              "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11701520/",
              "snapshot_id": "s06",
              "char_start": 9200,
              "verified_on": "2026-11-14",
              "observed": "page",
              "source_work": {
                "title": "KEGG: biological systems database as a model of the real world",
                "authors_or_org": "Kanehisa M, Furumichi M, Sato Y, Matsuura Y, Ishiguro-Watanabe M (Nucleic Acids Research)",
                "date": "2025-01-01",
                "date_as_written": "2025-01-01",
                "source_type": "peer-reviewed-paper",
                "open_access": true,
                "doi_or_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11701520/"
              }
            }
          ]
        }
      ]
    },
    "access_methods": [
      {
        "method": "web-api",
        "url": "https://www.kegg.jp/kegg/rest/",
        "formats": [],
        "limits": [
          {
            "text": {
              "en": "The text asks users to limit API calls to 3 times per second, otherwise access will be blocked.",
              "zh": "文本要求用户将 API 调用限制为每秒最多 3 次，否则访问将被阻止。"
            },
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "Please limit your API calls up to 3 times per second. Otherwise, your access will be blocked.",
                "url": "https://www.kegg.jp/kegg/rest/",
                "snapshot_id": "s04",
                "char_start": 790,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          },
          {
            "text": {
              "en": "The KEGG API at rest.kegg.jp is made available only for academic use by academic users.",
              "zh": "rest.kegg.jp 上的 KEGG API 仅向学术用户提供学术用途。"
            },
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "Restriction: KEGG API at rest.kegg.jp is made available only for academic use by academic users.",
                "url": "https://www.kegg.jp/kegg/rest/",
                "snapshot_id": "s04",
                "char_start": 600,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        ],
        "terms": {
          "same_as_card_license": false,
          "own_terms": {
            "commercial_use": "conditional",
            "redistribution": "unstated",
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "Restriction: KEGG API at rest.kegg.jp is made available only for academic use by academic users. Non-academic users are requested to follow the guidline shown in Non-academic use of KEGG .",
                "url": "https://www.kegg.jp/kegg/rest/",
                "snapshot_id": "s04",
                "char_start": 600,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        },
        "reachable": {
          "status": 200,
          "checked_on": "2026-11-14"
        }
      },
      {
        "method": "bulk-download",
        "url": "https://www.kegg.jp/kegg/download/",
        "formats": [],
        "limits": [
          {
            "text": {
              "en": "The KEGG FTP site for academic users is available to subscribers only.",
              "zh": "面向学术用户的 KEGG FTP 站点仅向订阅者开放。"
            },
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "The KEGG FTP site for academic users is available to subscribers only.",
                "url": "https://www.kegg.jp/kegg/download/",
                "snapshot_id": "s10",
                "char_start": 41,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "browser-agent"
              }
            ]
          }
        ],
        "terms": {
          "same_as_card_license": false,
          "own_terms": {
            "commercial_use": "unstated",
            "redistribution": "unstated",
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "The KEGG FTP site for academic users is available to subscribers only.",
                "url": "https://www.kegg.jp/kegg/download/",
                "snapshot_id": "s10",
                "char_start": 41,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "browser-agent"
              }
            ]
          }
        },
        "reachable": null
      },
      {
        "method": "web-ui-only",
        "url": "https://www.kegg.jp/",
        "formats": [],
        "limits": [
          {
            "text": {
              "en": "Academic users who use KEGG to provide services are requested to obtain an academic service provider license, which is included in the KEGG FTP academic subscription.",
              "zh": "利用 KEGG 提供服务的学术用户被要求获得学术服务提供者许可证，该许可证包含在 KEGG FTP 学术订阅中。"
            },
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "Academic users who utilize KEGG for providing services are requested to obtain an academic service provider license, which is included in the KEGG FTP academic subscription .",
                "url": "https://www.kegg.jp/kegg/legal.html",
                "snapshot_id": "s02",
                "char_start": 539,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        ],
        "terms": {
          "same_as_card_license": true,
          "own_terms": null
        },
        "reachable": {
          "status": 200,
          "checked_on": "2026-11-14"
        }
      },
      {
        "method": "web-ui-only",
        "url": "https://www.kegg.jp/kegg/legal.html",
        "formats": [],
        "limits": [],
        "terms": {
          "same_as_card_license": true,
          "own_terms": null
        },
        "statement": {
          "text": {
            "en": "Academic users may use the KEGG website freely; academic service providers need a licence included in the FTP academic subscription.",
            "zh": "学术用户可免费使用 KEGG 网站；用 KEGG 提供服务的学术用户需取得包含在 FTP 学术订阅中的服务许可。"
          },
          "evidence": [
            {
              "location": "dataset-page",
              "excerpt": "Academic users who utilize KEGG for providing services are requested to obtain an academic service provider license, which is included in the KEGG FTP academic subscription .",
              "url": "https://www.kegg.jp/kegg/legal.html",
              "snapshot_id": "s07",
              "char_start": 572,
              "verified_on": "2026-11-14",
              "observed": "page",
              "source_work": {
                "title": "KEGG Copyright and Disclaimer",
                "authors_or_org": "Kanehisa Laboratories (KEGG)",
                "date": "2024-10-01",
                "date_as_written": "2024-10-01",
                "source_type": "official-page",
                "open_access": true,
                "doi_or_url": "https://www.kegg.jp/kegg/legal.html"
              }
            }
          ]
        },
        "reachable": {
          "status": 200,
          "checked_on": "2026-11-14"
        }
      },
      {
        "method": "web-ui-only",
        "url": "https://www.kegg.jp/kegg/rest/",
        "formats": [],
        "limits": [],
        "terms": {
          "same_as_card_license": true,
          "own_terms": null
        },
        "statement": {
          "text": {
            "en": "API call rate limit: up to 3 per second.",
            "zh": "API 调用频率上限：每秒 3 次。"
          },
          "evidence": [
            {
              "location": "dataset-page",
              "excerpt": "Please limit your API calls up to 3 times per second.",
              "url": "https://www.kegg.jp/kegg/rest/",
              "snapshot_id": "s08",
              "char_start": 1019,
              "verified_on": "2026-11-14",
              "observed": "page",
              "source_work": {
                "title": "KEGG API",
                "authors_or_org": "Kanehisa Laboratories (KEGG)",
                "date": null,
                "date_as_written": null,
                "source_type": "official-page",
                "open_access": true,
                "doi_or_url": "https://www.kegg.jp/kegg/rest/"
              }
            }
          ]
        },
        "reachable": {
          "status": 200,
          "checked_on": "2026-11-14"
        }
      }
    ],
    "versioning": {
      "latest": {
        "label": "Release 120.0",
        "released_on": "2026-10-01",
        "statement": {
          "text": {
            "en": "The release notes list Release 120.0 dated October 1, 2026.",
            "zh": "发布说明列出发布于 2026 年 10 月 1 日的 Release 120.0。"
          },
          "evidence": [
            {
              "location": "api-doc",
              "excerpt": "Release 120.0, October 1, 2026",
              "url": "https://www.kegg.jp/kegg/docs/relnote.html",
              "snapshot_id": "s03",
              "char_start": 601,
              "verified_on": "2026-11-13",
              "observed": "page",
              "captured_by": "pipeline"
            }
          ]
        }
      },
      "update_cycle": {
        "cycle": "weekly",
        "statement": {
          "text": {
            "en": "The FTP site is updated weekly and contains the entire set of KEGG data, as summarized in the Readme files.",
            "zh": "该 FTP 站点每周更新，包含整套 KEGG 数据，并按以下 Readme 文件汇总。"
          },
          "evidence": [
            {
              "location": "dataset-page",
              "excerpt": "The weekly updated FTP site contains the entire set of KEGG data as summarized in the following Readme files.",
              "url": "https://www.kegg.jp/kegg/download/",
              "snapshot_id": "s10",
              "char_start": 129,
              "verified_on": "2026-11-13",
              "observed": "page",
              "captured_by": "browser-agent"
            }
          ]
        }
      },
      "breaking_changes": [
        {
          "version": "Release 118.2",
          "date": "2026-06-01",
          "kind": "other",
          "statement": {
            "text": {
              "en": "The reaction module (rmodule) dataset was moved from the MODULE database to the REACTION database.",
              "zh": "反应模块（rmodule）数据集已从 MODULE 数据库移至 REACTION 数据库。"
            },
            "evidence": [
              {
                "location": "api-doc",
                "excerpt": "The reaction module (rmodule) dataset has been moved from the MODULE database to the REACTION database.",
                "url": "https://www.kegg.jp/kegg/docs/relnote.html",
                "snapshot_id": "s03",
                "char_start": 2172,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        },
        {
          "version": "Release 109.0",
          "date": "2024-01-01",
          "kind": "identifier",
          "statement": {
            "text": {
              "en": "The term \"Virus ortholog cluster (Voc)\" was changed to \"Virus ortholog group (Vog)\" to distinguish it from clusters of positionally correlated genes along the chromosome.",
              "zh": "术语“Virus ortholog cluster (Voc)”已改为“Virus ortholog group (Vog)”，以区别于染色体上位置相关的基因簇，例如基因簇、KO 簇和 Vog 簇。"
            },
            "evidence": [
              {
                "location": "api-doc",
                "excerpt": "The term \"Virus ortholog cluster (Voc)\" has been changed to \"Virus ortholog group (Vog)\" in order to distinguish from clusters of positionally correlated genes along the chromosome, such as gene clusters, KO clusters and Vog clusters.",
                "url": "https://www.kegg.jp/kegg/docs/relnote.html",
                "snapshot_id": "s03",
                "char_start": 8929,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        },
        {
          "version": "KEGG API",
          "date": "2022-06-01",
          "kind": "access",
          "statement": {
            "text": {
              "en": "The API update history lists that the service moved from HTTP to HTTPS on June 1, 2022.",
              "zh": "API 更新历史列出该服务于 2022 年 6 月 1 日从 HTTP 迁移到 HTTPS。"
            },
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "June 1, 2022 Moved from HTTP to HTTPS",
                "url": "https://www.kegg.jp/kegg/rest/",
                "snapshot_id": "s04",
                "char_start": 1312,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        },
        {
          "version": "KEGG API",
          "date": "2016-10-01",
          "kind": "content-removed",
          "statement": {
            "text": {
              "en": "The API update history states that RPAIR was removed on October 1, 2016.",
              "zh": "API 更新历史说明 RPAIR 于 2016 年 10 月 1 日被移除。"
            },
            "evidence": [
              {
                "location": "dataset-page",
                "excerpt": "October 1, 2016 RPAIR removed",
                "url": "https://www.kegg.jp/kegg/rest/",
                "snapshot_id": "s04",
                "char_start": 1673,
                "verified_on": "2026-11-13",
                "observed": "page",
                "captured_by": "pipeline"
              }
            ]
          }
        }
      ],
      "history_url": null
    },
    "known_defects": [],
    "fit": {
      "suited_for": [
        {
          "text": {
            "en": "The text states that academic users may freely use the KEGG website at the kegg.jp address or its GenomeNet mirror.",
            "zh": "文本说明学术用户可以自由使用 kegg.jp 地址上的 KEGG 网站或其 GenomeNet 镜像站点。"
          },
          "evidence": [
            {
              "location": "dataset-page",
              "excerpt": "Academic users may freely use the KEGG website at https://www.kegg.jp/ or its mirror site at GenomeNet https://www.genome.jp/kegg/ .",
              "url": "https://www.kegg.jp/kegg/legal.html",
              "snapshot_id": "s02",
              "char_start": 406,
              "verified_on": "2026-11-13",
              "observed": "page",
              "captured_by": "pipeline"
            }
          ]
        }
      ],
      "not_suited_for": [
        {
          "text": {
            "en": "The text states that non-academic use of KEGG requires a commercial license.",
            "zh": "文本说明 KEGG 的非学术用途需要商业许可证。"
          },
          "evidence": [
            {
              "location": "dataset-page",
              "excerpt": "Non-academic use of KEGG requires a commercial license.",
              "url": "https://www.kegg.jp/kegg/legal.html",
              "snapshot_id": "s02",
              "char_start": 850,
              "verified_on": "2026-11-13",
              "observed": "page",
              "captured_by": "pipeline"
            }
          ]
        }
      ]
    },
    "commercial_access": {
      "route": "contact-publisher",
      "url": null,
      "statement": {
        "text": {
          "en": "The text directs users to contact Pathway Solutions, which operates the KEGG FTP sites and a KEGG mirror website, for license agreements.",
          "zh": "文本要求用户联系运营 KEGG FTP 站点和 KEGG 镜像网站的 Pathway Solutions 以获取许可协议。"
        },
        "evidence": [
          {
            "location": "dataset-page",
            "excerpt": "Please contact Pathway Solutions , which operates KEGG FTP sites and a KEGG mirror website, for license agreements.",
            "url": "https://www.kegg.jp/kegg/legal.html",
            "snapshot_id": "s02",
            "char_start": 906,
            "verified_on": "2026-11-13",
            "observed": "page",
            "captured_by": "pipeline"
          }
        ]
      }
    },
    "completeness": {
      "core_complete": true,
      "literature_defects": 0,
      "reachable_access": 4,
      "meets_practical_bar": false,
      "gaps": [
        {
          "field": "known_defects",
          "note": "未找到有出处的说明 / no sourced statement found"
        }
      ]
    }
  },
  "access_recipe": {
    "verified_on": "2026-11-14",
    "latest_release": {
      "version": "120.0",
      "date": "October 1, 2026",
      "evidence": {
        "excerpt": "Release 120.0, October 1, 2026",
        "snapshot_id": "s03",
        "url": "https://www.kegg.jp/kegg/docs/relnote.html"
      }
    },
    "files": [],
    "api": [],
    "registration": {
      "required": true,
      "url": "https://www.pathway.jp/en/academic.html",
      "steps": [],
      "evidence": {
        "excerpt": "The KEGG FTP site for academic users is available to subscribers only.",
        "snapshot_id": "s10",
        "url": "https://www.kegg.jp/kegg/download/"
      }
    },
    "bulk_download": [],
    "gaps": [
      "no direct file address was found on the official pages we hold",
      "the official pages we hold publish no checksum for the files; none was computed (we do not download data files)"
    ],
    "license_note": {
      "license_status": "restricted",
      "text": "Use according to the terms of the official source; this recipe does not say the data can be used freely."
    }
  },
  "_links": {
    "text": "Continue in this database. This record is one of 109 processed and verified records (datasets, data resources and open models). To find others, call `https://mcp.mdexa.com/v1/datasets?q=<words>` or connect the MCP server at `https://mcp.mdexa.com/mcp`; no key is needed for 20 calls per minute. Rows are under 1 KB; an empty result means \"not listed\". For a list of items, one batch check (free account) returns a report. Guide: /agents.md. Similar records: AlphaFold Protein Structure Database (https://mdexa.com/datasets/alphafold-db/); GEO (https://mdexa.com/datasets/geo/); gnomAD (https://mdexa.com/datasets/gnomad/).",
    "records": 109,
    "search": {
      "template": "https://mcp.mdexa.com/v1/datasets?q={words}",
      "example": "https://mcp.mdexa.com/v1/datasets?q=binding%20affinity"
    },
    "mcp": "https://mcp.mdexa.com/mcp",
    "anonymous_calls_per_minute": 20,
    "guide": "https://mdexa.com/agents.md",
    "faq": "https://mdexa.com/developers/faq/",
    "similar": [
      {
        "name": "AlphaFold Protein Structure Database",
        "url": "https://mdexa.com/datasets/alphafold-db/",
        "json": "https://mdexa.com/datasets/alphafold-db.json"
      },
      {
        "name": "GEO",
        "url": "https://mdexa.com/datasets/geo/",
        "json": "https://mdexa.com/datasets/geo.json"
      },
      {
        "name": "gnomAD",
        "url": "https://mdexa.com/datasets/gnomad/",
        "json": "https://mdexa.com/datasets/gnomad.json"
      }
    ]
  }
}