# Evo 2

Evo 2. Code: Apache-2.0; weights: Apache-2.0. Last verified 2026-11-14. Query directly over MCP or API.

## Code license

Permissive · Apache-2.0
Commercial use: Yes · derivatives: Yes · redistribution: Yes

> Apache License
https://raw.githubusercontent.com/ArcInstitute/evo2/main/LICENSE (2026-11-13)

## Weights license

Permissive · Apache-2.0
Commercial use: Yes · derivatives: Yes · redistribution: Yes

> License: apache-2.0
https://huggingface.co/arcinstitute/evo2_7b (2026-11-13)

## Commercial use of Evo 2

- Code: Yes
- Weights: Yes
The code license and the weights license stand apart; a verdict on one does not carry over to the other.
Verdicts record what sources state and are not legal advice.

## Training data

- The README states that Evo 2 was trained autoregressively on OpenGenome2, a dataset containing 8.8 trillion tokens from all domains of life.
  > Evo 2 was trained autoregressively on [OpenGenome2](https://huggingface.co/datasets/arcinstitute/opengenome2), a dataset containing 8.8 trillion tokens from all domains of life.
  https://raw.githubusercontent.com/ArcInstitute/evo2/main/README.md (2026-11-13)
- The README lists an evo2_7b_microviridae checkpoint described as a 7B parameter base model fine-tuned on Microviridae genomes.
  > | `evo2_7b_microviridae` | 7B parameter base model fine-tuned on Microviridae genomes |
  https://raw.githubusercontent.com/ArcInstitute/evo2/main/README.md (2026-11-13)

## How to run

- Weights download: https://huggingface.co/arcinstitute
- Hosted API: https://build.nvidia.com/arc/evo2-40b

## Versions

- v0.5.0: code Apache-2.0, weights Apache-2.0

## No sourced statement yet

Limits on outputs, Overlap with benchmarks, Known defects and misuse

https://mdexa.com/models/evo2/

## Continue in this database

This record is one of 109 processed and verified records (datasets, data resources and open models). To find others, call `https://mcp.mdexa.com/v1/datasets?q=<words>` or connect the MCP server at `https://mcp.mdexa.com/mcp`; no key is needed for 20 calls per minute. Rows are under 1 KB; an empty result means "not listed". For a list of items, one batch check (free account) returns a report. Guide: /agents.md. Similar records: ESM-2 (https://mdexa.com/models/esm2/); ESMFold (https://mdexa.com/models/esmfold/); AlphaFold 3 (https://mdexa.com/models/alphafold3/).