# Reactome

许可证声明：宽松（CC0-1.0）；本站处理：只链接原出处。第二遍复核：license_status: looser by the source's own words (looser-explicit): 【标准许可误作自定义条款】许可协议第1条c款写明全部数据及其派生文件采用 CC0，可复制、修改、分发，甚至用于商业，无需许可；插图等为 CC BY 4.0；软件为 Apache 2.0。唯一的"特别许可"针对 FoamTree 软件的本地安装，属配套软件（第21条），不参与数据状态。"不同意即不得使用"是接受条款，不是甲类限制。数据部分没有甲类句，按原文应为 permissive（标识 CC0-1.0），插图部分 CC BY 4.0 带 attribution；比拟定更宽，原文明示，交采纳环节放宽。；commercial_use: looser by the source's own words (looser-explicit): 原文明示数据"even for commercial purposes"可用，按原文应为 yes。；derivatives: looser by the source's own words (looser-explicit): 原文明示可修改（modify），按原文应为 yes。；redistribution: looser by the source's own words (looser-explicit): 原文明示可分发（distribute），按原文应为 yes。。

- 能否商用：是 · 能否改编：是 · 能否再分发：是 · Mdexa 提供文件：否
- 许可证状态：宽松 (CC0-1.0)
- Mdexa 处理：只链接 — 许可证状态：宽松，按公开规则判定并经第二遍模型复核。仅链接。
- 最近核实：2026-11-14
- 信息卡：https://mdexa.com/zh/datasets/reactome/

## 关键事实

- 领域：基因与组学
- 内容类型：结构化数据库
- 规模：—
- 语言：英文
- 模态：文本
- 发布方：Reactome
- 年份：—

## Reactome 是否允许商业使用

- 商业使用：是。
整体结论取各部分中最严的一项；各部分许可不同，见下列。
- 许可状态：宽松。
- 条件：署名、保留声明
- 许可部分：Pathway Illustrations, Icon Library, Art, and Branding Materials — 宽松 (CC-BY-4.0)
- 许可部分：Software and Code — 宽松 (Apache-2.0)
- 许可部分：Data — 宽松 (CC0-1.0)
- 许可部分：This Reactome — 宽松 (CC-BY-4.0)
- 许可部分：FoamTree (Voronoi Treemaps) — 宽松 (NOASSERTION)
结论仅记录来源所述，不构成法律意见。

## Reactome 许可证证据

各部分均宽松，条件取各部分的并集

- **使用条款页**：在快照 s02（page）中找到的声明 — "This License Agreement (the “Agreement”) governs the use of the Reactome database and its contents, including all data, graphics, software, and other materials associated therewith." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "If you do not agree with the terms of this Agreement, you may not use Reactome." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "User agrees that the content on Reactome is governed by various open-source licenses and agrees to adhere to applicable license terms as follows:" — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页** — CC-BY-4.0：在快照 s02（page）中找到的声明 — "This Reactome content is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0)" — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "User may copy, modify, and distribute these materials, provided that appropriate credit is given, a link to the license is included, and any modifications made by User are clearly indicated." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页** — Apache-2.0：在快照 s02（page）中找到的声明 — "all Reactome software is licensed under the Apache License 2.0" — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "Individual repositories are marked with the appropriate licensing requirements, and User must ensure their intended use is compliant with the relevant license, as applicable." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页** — CC0-1.0：在快照 s02（page）中找到的声明 — "All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0)" — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "Attribution is encouraged but not required." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "Notwithstanding the Applicable Open-Source Licenses set out in Section 1 above, User agrees to the application of Special Licenses to certain Reactome content as follows:" — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "The FoamTree software, used to construct the ReacFoam genome-wide pathway overview, is provided under license by Carrot Search, Inc." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "Images and analyses generated on the Reactome website using FoamTree software are free to use with no restriction." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "For local installations of the Reactome, User must either: i) use the free, fully functional demo version of the FoamTree software included with Reactome, which adds a promotional logo to one of the cells of the visualization; or ii) obtain their own license from Carrot Search directly." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "Reactome is provided “as is” and “as available” without any warranties of any kind, either express or implied." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "Users must comply with all applicable licensing requirements and ensure that their access and/or use of Reactome content is consistent with the terms of this Agreement." — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "© 2026" — https://reactome.org/license (2026-11-13; 亲自打开)
- **使用条款页**：在快照 s02（page）中找到的声明 — "This Reactome content is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0) ." — https://reactome.org/license (2026-11-13; 亲自打开)
- **数据集页面** — CC0-1.0：在快照 s02（page）中找到：Part "Data" — "c) Data : All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0) ." — https://reactome.org/license (2026-11-13; 亲自打开)
- **数据集页面** — CC-BY-4.0：在快照 s02（page）中找到：Part "Pathway Illustrations, Icon Library, Art" — "a) Pathway Illustrations, Icon Library, Art, and Branding Materials . This Reactome content is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0) ." — https://reactome.org/license (2026-11-13; 亲自打开)

## 来源与血缘

—

## Reactome 已知问题

—

## 预检

未预检（数据未入库）。

## Reactome 下载、接口与获取方式

Mdexa 站内不提供文件。原始出处：
- https://reactome.org/
- https://reactome.org/license

### 取用配方

- 最新版本：V98

## Reactome 引用格式

原始资料没有给出推荐引用文本。

## 机器可读

- JSON: https://mdexa.com/datasets/reactome.json
- 2026-11-14 2026-11-14 上架。按公开规则判定，经二次核对后收录。两遍判定不一致，卡上取较严的读法：第二遍复核：license_status: looser by the source's own words (looser-explicit): 【标准许可误作自定义条款】许可协议第1条c款写明全部数据及其派生文件采用 CC0，可复制、修改、分发，甚至用于商业，无需许可；插图等为 CC BY 4.0；软件为 Apache 2.0。唯一的"特别许可"针对 FoamTree 软件的本地安装，属配套软件（第21条），不参与数据状态。"不同意即不得使用"是接受条款，不是甲类限制。数据部分没有甲类句，按原文应为 permissive（标识 CC0-1.0），插图部分 CC BY 4.0 带 attribution；比拟定更宽，原文明示，交采纳环节放宽。；commercial_use: looser by the source's own words (looser-explicit): 原文明示数据"even for commercial purposes"可用，按原文应为 yes。；derivatives: looser by the source's own words (looser-explicit): 原文明示可修改（modify），按原文应为 yes。；redistribution: looser by the source's own words (looser-explicit): 原文明示可分发（distribute），按原文应为 yes。

## 实用信息

### 内容范围

- 页面说明 Reactome 包含 16,503 个人类反应，组织为 2,889 条通路，涉及由 11,496 个不同人类基因编码的 32,565 个蛋白质及蛋白质修饰形式、16,325 个复合物、2,178 个小分子和 1,103 种药物。
  > Reactome comprises 16,503 human reactions organized into 2,889 pathways involving 32,565 proteins and modified forms of proteins encoded by 11,496 different human genes, 16,325 complexes, 2,178 small molecules, and 1,103 drugs.
  https://reactome.org/about/news (2026-11-13)
- 页面说明这些反应被投射到 83,732 个直系同源蛋白质上，在 14 个非人类物种中创建了 20,751 条直系同源通路。
  > We have projected these reactions onto 83,732 orthologous proteins, creating 20,751 orthologous pathways in 14 non-human species.
  https://reactome.org/about/news (2026-11-13)

### 标识符

- 下载页面列出了稳定标识符数据库。
  > Stable identifiers database
  https://reactome.org/download-data (2026-11-13)
- 页面列出了一个条目：UniProt to pathways。
  > UniProt to pathways
  https://reactome.org/download-data (2026-11-13)
- 页面列出了一个条目：ChEBI to pathways。
  > ChEBI to pathways
  https://reactome.org/download-data (2026-11-13)
- 页面列出了一个条目：ENSEMBL to pathways。
  > ENSEMBL to pathways
  https://reactome.org/download-data (2026-11-13)
- 页面列出了一个条目：miRBase to pathways。
  > miRBase to pathways
  https://reactome.org/download-data (2026-11-13)
- 页面列出了一个条目：NCBI to pathways。
  > NCBI to pathways
  https://reactome.org/download-data (2026-11-13)
- 页面列出了一个条目：GtoP to pathways。
  > GtoP to pathways
  https://reactome.org/download-data (2026-11-13)
- 页面列出了一个条目：Reactome to OMIM。
  > Reactome to OMIM
  https://reactome.org/download-data (2026-11-13)
- 页面列出了一个条目：BioModels to Pathways。
  > BioModels to Pathways
  https://reactome.org/download-data (2026-11-13)

### 取用方式

- 仅网页界面：https://reactome.org/about/news
- 批量下载：https://reactome.org/download-data
- 数据库转储：https://reactome.org/download-data
- 仅网页界面：https://reactome.org/license

### 版本

- 页面说明 Zenodo 下载目录针对每个 Reactome 版本按季度创建，从版本 89（06/2024）开始，包含下载文件。
  > The Zenodo download directory is created for every Reactome (reactome.org) release quarterly, starting from version 89 (06/2024), containing download files.
  https://reactome.org/download-data (2026-11-13)
- 页面指出，自 Reactome V94 起，Events in BioPAX level 2 format 将不再提供。
  > Note: As of Reactome V94, the “Events in BioPAX level 2 format" will no longer be available.
  https://reactome.org/download-data (2026-11-13)
- 页面指出，自 Reactome V94 起，Protégé 2.0 ontology files 将不再提供。
  > Note: As of Reactome V94, the “Protégé 2.0 ontology files” will no longer be available.
  https://reactome.org/download-data (2026-11-13)

### 已知缺陷与常见误用

- 页面说明，复合物的所有蛋白质组分之间都会推断相互作用；为限制假阳性推断的产成，仅考虑蛋白质组分不超过四个的复合物。
  > Interactions are inferred between all protein components of a complex. To limit the creation of false-positive inferences, only complexes with four or fewer protein components are considered.
  https://reactome.org/download-data (2026-11-13)

### 适合的任务

- 页面说明这些服务和软件工具面向生物学家、生物信息学家和软件开发人员设计。
  > Our services and software tools are designed for biologists, bioinformaticians, and software developers.
  https://reactome.org/about/news (2026-11-13)
- 页面说明 Reactome FIViz 应用和 ReactomeGSA 软件包提供用于多组学数据分析的工具。
  > The Reactome FIViz app and ReactomeGSA package provide tools for multi-omics data analysis.
  https://reactome.org/about/news (2026-11-13)

### 尚无有出处的说明

最新版本, 不适合的任务, 商业授权入口

## 在本库继续查找

本条目是 109 条已处理并核实的记录之一（数据集、数据资源与开源模型）。查找其他条目：调用 `https://mcp.mdexa.com/v1/datasets?q=<关键词>`，或连接 MCP 服务 `https://mcp.mdexa.com/mcp`；每分钟 20 次以内无需密钥。每行返回不到 1 KB；空结果即"数据库未收录"。核对一份清单：一次批量核对（免费账号）即返回报告。说明：/agents.md。相似条目：STRING (https://mdexa.com/zh/datasets/string/)；AlphaFold Protein Structure Database (https://mdexa.com/zh/datasets/alphafold-db/)；GEO (https://mdexa.com/zh/datasets/geo/)。
