{
  "slug": "openfold3",
  "name": "OpenFold3",
  "kind": "co-folding",
  "publisher": "OpenFold consortium",
  "tier": "verified",
  "license_code": {
    "status": "permissive",
    "spdx": "Apache-2.0",
    "custom_license": false,
    "commercial_use": "yes",
    "derivatives": "yes",
    "redistribution": "yes",
    "license_conditions": [
      "notice-required"
    ],
    "requires_application": false,
    "evidence": [
      {
        "location": "repo-license",
        "excerpt": "Apache License",
        "url": "https://raw.githubusercontent.com/aqlaboratory/openfold-3/main/LICENSE",
        "snapshot_id": "s01",
        "char_start": 34,
        "verified_on": "2026-11-13",
        "observed": "page",
        "captured_by": "pipeline"
      }
    ]
  },
  "license_weights": {
    "status": "permissive",
    "spdx": "Apache-2.0",
    "custom_license": false,
    "commercial_use": "yes",
    "derivatives": "yes",
    "redistribution": "yes",
    "license_conditions": [
      "notice-required"
    ],
    "requires_application": false,
    "evidence": [
      {
        "location": "dataset-page",
        "excerpt": "The OpenFold3-preview model is released under Apache 2.0 license.",
        "url": "https://huggingface.co/OpenFold/OpenFold3",
        "snapshot_id": "s08",
        "char_start": 534,
        "verified_on": "2026-11-13",
        "observed": "page",
        "captured_by": "pipeline"
      }
    ]
  },
  "last_verified": "2026-11-14",
  "schema_version": "2.0",
  "record_type": "model",
  "official_urls": {
    "repository_or_release": "https://github.com/aqlaboratory/openfold-3",
    "weights_page": "https://huggingface.co/OpenFold/OpenFold3",
    "paper": null,
    "license_file": "https://raw.githubusercontent.com/aqlaboratory/openfold-3/main/LICENSE"
  },
  "version_history": [
    {
      "version": "0.4.2",
      "released_on": null,
      "code_license": "Apache-2.0",
      "weights_license": "Apache-2.0",
      "changed": "no-license-change",
      "note": null,
      "evidence": [
        {
          "location": "readme",
          "excerpt": "version = {0.4.2}",
          "url": "https://raw.githubusercontent.com/aqlaboratory/openfold-3/HEAD/README.md",
          "snapshot_id": "s03",
          "char_start": 8417,
          "verified_on": "2026-11-13",
          "observed": "page",
          "captured_by": "pipeline"
        }
      ]
    }
  ],
  "output_restrictions": [],
  "training_data": [
    {
      "resource": "MGnify-based 13M-sequence distillation dataset",
      "slug": null,
      "role": "pretraining",
      "cutoff_date": null,
      "cutoff_stated": false,
      "statement": {
        "text": {
          "en": "The README states that the full training data for reproducing OpenFold3-preview includes a reproduction of the MGnify-based 13M-sequence distillation dataset described in the AlphaFold3 paper.",
          "zh": "README 说明，用于复现 OpenFold3-preview 的完整训练数据包括对 AlphaFold3 论文中所述基于 MGnify 的 1300 万序列蒸馏数据集的复现。"
        },
        "evidence": [
          {
            "location": "readme",
            "excerpt": "We provide the full training data for reproducing OpenFold3-preview, including our reproduction of the MGnify-based 13M-sequence distillation dataset described in the AlphaFold3 paper.",
            "url": "https://raw.githubusercontent.com/aqlaboratory/openfold-3/HEAD/README.md",
            "snapshot_id": "s03",
            "char_start": 2872,
            "verified_on": "2026-11-13",
            "observed": "page",
            "captured_by": "pipeline"
          }
        ]
      }
    },
    {
      "resource": "PDB",
      "slug": "rcsb-pdb",
      "role": "other",
      "cutoff_date": null,
      "cutoff_stated": false,
      "statement": {
        "text": {
          "en": "OpenBind-0 was trained on PDB data through June 2025 (cutoff 30 June 2025).",
          "zh": "OpenBind-0 训练数据为截至 2025 年 6 月的 PDB（截止 2025-06-30）。"
        },
        "evidence": [
          {
            "location": "official-change-notice",
            "excerpt": "OB0 is trained on data from the Protein Data Bank (PDB) through June 2025",
            "url": "https://openbind.uk/news/blog-openbind-0-advancing-open-molecular-structure-prediction/",
            "snapshot_id": "s11",
            "char_start": 1864,
            "verified_on": "2026-11-13",
            "observed": "page",
            "source_work": {
              "title": "Blog: OpenBind-0",
              "authors_or_org": "OpenBind / OpenFold consortium",
              "date": "2026-08-21",
              "date_as_written": "2026-08-21",
              "source_type": "official-change-notice",
              "open_access": true,
              "doi_or_url": "https://openbind.uk/news/blog-openbind-0-advancing-open-molecular-structure-prediction/"
            }
          }
        ]
      }
    },
    {
      "resource": "MGnify",
      "slug": null,
      "role": "other",
      "cutoff_date": null,
      "cutoff_stated": false,
      "statement": {
        "text": {
          "en": "Full training data for reproducing OpenFold3-preview are provided, including a reproduction of the MGnify-based 13M-sequence distillation set described in the AF3 paper.",
          "zh": "提供复现 OpenFold3-preview 的完整训练数据，包括对 AF3 论文所述基于 MGnify 的 1300 万序列蒸馏集的复现。"
        },
        "evidence": [
          {
            "location": "dataset-page",
            "excerpt": "including our reproduction of the MGnify-based 13M-sequence distillation dataset described in the AlphaFold3 paper.",
            "url": "https://github.com/aqlaboratory/openfold-3/blob/main/README.md",
            "snapshot_id": "s09",
            "char_start": 2941,
            "verified_on": "2026-11-13",
            "observed": "page",
            "source_work": {
              "title": "openfold-3 README — Datasets",
              "authors_or_org": "AlQuraishi Lab / OpenFold consortium",
              "date": null,
              "date_as_written": null,
              "source_type": "official-page",
              "open_access": true,
              "doi_or_url": "https://github.com/aqlaboratory/openfold-3/blob/main/README.md"
            }
          }
        ]
      }
    }
  ],
  "benchmark_overlap": [],
  "access": [
    {
      "method": "application-required",
      "url": "https://huggingface.co/OpenFold/OpenFold3",
      "terms_differ_from_weights_license": false,
      "own_terms": null
    },
    {
      "method": "hosted-api",
      "url": "https://docs.api.nvidia.com/nim/reference/openfold-openfold3",
      "terms_differ_from_weights_license": false,
      "own_terms": null
    }
  ],
  "conflicts": [],
  "hardware_notes": [
    {
      "text": {
        "en": "Documentation mentions multi-GPU distributed prediction and a low-memory mode for memory-constrained GPUs; no minimum GPU spec was found.",
        "zh": "文档提到多 GPU 分布式预测与显存受限时的低显存模式；未见最低 GPU 规格。"
      },
      "evidence": [
        {
          "location": "dataset-page",
          "excerpt": "Custom settings for memory constrained GPU resources",
          "url": "https://openfold-3.readthedocs.io/en/latest/",
          "snapshot_id": "s12",
          "char_start": 2453,
          "verified_on": "2026-11-13",
          "observed": "page",
          "source_work": {
            "title": "OpenFold3-preview documentation",
            "authors_or_org": "OpenFold Team",
            "date": null,
            "date_as_written": null,
            "source_type": "official-page",
            "open_access": true,
            "doi_or_url": "https://openfold-3.readthedocs.io/en/latest/"
          }
        }
      ]
    }
  ],
  "known_defects": [],
  "fit": {
    "suited_for": [
      {
        "text": {
          "en": "The maintainers write that OpenBind-0 is advised over OpenFold3-preview2 for everyday usage.",
          "zh": "维护方写明日常使用建议用 OpenBind-0，而不是 OpenFold3-preview2。"
        },
        "evidence": [
          {
            "location": "dataset-page",
            "excerpt": "We reccomend using the OpenBind-0 model over OpenFold3-preview2 for everyday usage.",
            "url": "https://github.com/aqlaboratory/openfold-3/blob/main/README.md",
            "snapshot_id": "s09",
            "char_start": 1923,
            "verified_on": "2026-11-13",
            "observed": "page",
            "source_work": {
              "title": "openfold-3 README",
              "authors_or_org": "AlQuraishi Lab / OpenFold consortium",
              "date": null,
              "date_as_written": null,
              "source_type": "official-page",
              "open_access": true,
              "doi_or_url": "https://github.com/aqlaboratory/openfold-3/blob/main/README.md"
            }
          }
        ]
      }
    ],
    "not_suited_for": []
  },
  "gaps": [
    {
      "field": "output_restrictions",
      "note": "未找到有出处的说明 / no sourced statement found"
    },
    {
      "field": "benchmark_overlap",
      "note": "未找到有出处的说明 / no sourced statement found"
    },
    {
      "field": "known_defects",
      "note": "未找到有出处的说明 / no sourced statement found"
    }
  ],
  "completeness": {
    "core_complete": true
  },
  "changelog": [
    {
      "date": "2026-11-14",
      "change": {
        "en": "Added by the automated pipeline from stored page snapshots; every statement carries a verbatim quote.",
        "zh": "由自动流水线根据已存页面快照添加，每条陈述带逐字引文。"
      },
      "by": "pipeline"
    }
  ],
  "access_recipe": {
    "verified_on": "2026-11-14",
    "platform": "huggingface",
    "repo_id": "OpenFold/OpenFold3",
    "source": {
      "api_url": "https://huggingface.co/api/models/OpenFold/OpenFold3",
      "fetched_on": "2026-11-14"
    },
    "access_state": "gated",
    "files": [],
    "files_truncated": false,
    "commands": [],
    "registration": {
      "required": true,
      "url": "https://huggingface.co/OpenFold/OpenFold3",
      "steps": [
        "The repository is gated: an account and an access request on the repository page are needed (we do not bypass this)"
      ]
    },
    "version": {
      "commit": "33ffa390314567dd2d61bb635de52c7810e47056",
      "last_modified": "2026-05-26T09:32:47.000Z"
    },
    "license_note": {
      "license_status": "permissive",
      "text": "Use according to the terms of the official source; this recipe does not say the data can be used freely."
    },
    "gaps": [
      "the platform publishes no checksum for these files; none was computed (we do not download data files)"
    ]
  },
  "_links": {
    "text": "在本库继续查找。本条目是 109 条已处理并核实的记录之一（数据集、数据资源与开源模型）。查找其他条目：调用 `https://mcp.mdexa.com/v1/datasets?q=<关键词>`，或连接 MCP 服务 `https://mcp.mdexa.com/mcp`；每分钟 20 次以内无需密钥。每行返回不到 1 KB；空结果即\"数据库未收录\"。核对一份清单：一次批量核对（免费账号）即返回报告。说明：/agents.md。相似条目：AlphaFold 3 (https://mdexa.com/zh/models/alphafold3/)；Boltz (Boltz-1 and Boltz-2) (https://mdexa.com/zh/models/boltz/)；ESM C (https://mdexa.com/zh/models/esm-c/)。",
    "records": 109,
    "search": {
      "template": "https://mcp.mdexa.com/v1/datasets?q={words}",
      "example": "https://mcp.mdexa.com/v1/datasets?q=%E7%BB%93%E5%90%88%E4%BA%B2%E5%92%8C%E5%8A%9B"
    },
    "mcp": "https://mcp.mdexa.com/mcp",
    "anonymous_calls_per_minute": 20,
    "guide": "https://mdexa.com/zh/agents.md",
    "faq": "https://mdexa.com/zh/developers/faq/",
    "similar": [
      {
        "name": "AlphaFold 3",
        "url": "https://mdexa.com/zh/models/alphafold3/",
        "json": "https://mdexa.com/zh/models/alphafold3.json"
      },
      {
        "name": "Boltz (Boltz-1 and Boltz-2)",
        "url": "https://mdexa.com/zh/models/boltz/",
        "json": "https://mdexa.com/zh/models/boltz.json"
      },
      {
        "name": "ESM C",
        "url": "https://mdexa.com/zh/models/esm-c/",
        "json": "https://mdexa.com/zh/models/esm-c.json"
      }
    ]
  }
}