ESM C
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ESM C code and weights licenses
Code
- Commercial use
- Yes
- Derivatives
- Yes
- Redistribution
- Yes
raw.githubusercontent.com ·
Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the “Software”), to deal in the Software without restriction
https://raw.githubusercontent.com/evolutionaryscale/esm/main/LICENSE.md · Repository license file · checked 2026-11-13
raw.githubusercontent.com ·
Copyright 2026 Chan Zuckerberg Biohub, Inc.
https://raw.githubusercontent.com/Biohub/esm/main/LICENSE.md · Repository license file · checked 2026-11-13
Weights
- Commercial use
- unverified
- Derivatives
- unverified
- Redistribution
- unverified
huggingface.co ·
License: other
https://huggingface.co/EvolutionaryScale/esmc-300m-2024-12 · Dataset page · checked 2026-11-13
huggingface.co ·
"license:mit","license:other"
https://huggingface.co/biohub/ESMC-300M · Dataset page · checked 2026-11-13
Commercial use of ESM C
- Code
- Yes · Permissive
- Weights
- Unverified · Unverifiable
The code license and the weights license stand apart; a verdict on one does not carry over to the other. Quoted statements and their sources are in the license section above.
Verdicts record what sources state and are not legal advice.
Limits on outputs
- The model card's out-of-scope section prohibits any use barred by the Acceptable Use Policy.
huggingface.co ·
Any use that is prohibited by the Acceptable Use Policy
https://huggingface.co/biohub/ESMC-300M · Dataset page · checked 2026-11-13
Training data
- UniRef, MGnify, and the Joint Genome Institute (JGI) ESM C is trained on protein sequences from UniRef, MGnify, and the Joint Genome Institute (JGI).
evolutionaryscale.ai ·
ESM C is trained on protein sequences from UniRef, MGnify, and the Joint Genome Institute (JGI).
https://www.evolutionaryscale.ai/blog/esm-cambrian · Dataset page · checked 2026-11-13
- UniRef ESMC was trained on UniRef, MGnify and JGI sequences clustered at 70% identity (83M, 372M and 2B clusters respectively).
huggingface.co ·
ESMC was trained on protein sequences from UniRef, MGnify, and the Joint Genome Institute (JGI).
https://huggingface.co/biohub/ESMC-300M · Dataset page · checked 2026-11-13
Running ESM C
- Weights downloadhuggingface.co
- Hosted APIbiohub.ai
- Third-party hostinggithub.com
ESM C versions
- unspecified (2025-01-16): code —, weights —
github.com ·
ESM C 600M (incl weights)
https://github.com/Biohub/esm/blob/1b3e08025b/LICENSE.md · Dataset page · checked 2026-11-13
- unspecified (2025-01-16): code —, weights —
github.com ·
Just remember to maintain the same license terms and release under the ESM name.
https://github.com/Biohub/esm/blob/1b3e08025b/LICENSE.md · Dataset page · checked 2026-11-13
- 304 (2026-05-27): code —, weights —
github.com ·
Update esm repo for ESMC paper ( #304 )
https://github.com/Biohub/esm/commit/c94ed8d763 · Dataset page · checked 2026-11-13
ESM C official download addresses
- Repository or releasehttps://github.com/evolutionaryscale/esm
- Weights pagehttps://huggingface.co/EvolutionaryScale/esmc-300m-2024-12
- License filehttps://raw.githubusercontent.com/evolutionaryscale/esm/main/LICENSE.md
No sourced statement yet
Overlap with benchmarks